Season 21

The twenty-first season of the American medical drama Grey's Anatomy intensifies the narrative as a new generation of physicians steps into leadership roles. Lingering emotional fallout from the prior season shapes the trajectory of Grey Sloan while pivotal decisions redefine its future. In the wake of a devastating convenience-store shooting, chaos erupts at Grey Sloan. Ben faces a setback with his new emergency preparedness plan. Meredith and Nick return to Grey Sloan to care for a liver transplant patient. Jo and Link grapple with wedding plans as the big day arrives, with visitors in tow. Legacy characters alongside fresh faces continue to navigate life, loss, and medicine.