Big Top Pee-wee

Frances Bay

Mrs. Haynes

Randal Kleiser

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Paul Reubens

Pee-wee Herman

Benicio del Toro

Duke the Dog-Faced Boy

Kenneth Tobey

Sheriff

Lynne Marie Stewart

Zelda the Bearded Lady

Helen Siff

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Susan Tyrrell

Midge Montana

Joyce King

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Patricia M. Peters

Web Girl

Franco Columbu

Otto the Strongman

Joey Arias

Shim

Linda Montanti

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Penelope Ann Miller

Winnie

David Byrd

Deke

Kris Kristofferson

Mace Montana

Jack Murdock

Otis

Leo Gordon

Joe the Blacksmith (as Leo V. Gordon)

Vance Colvig

Clownie

Albert Henderson

Mr. Ryan

Dustin Diamond

Child - Deke

Valeria Golino

Gina Piccolapupula

Anne Seymour

Pearl

Wayne White

Vance the Pig (voice)

Mary Jackson

Mrs. Dill

Stephanie Hodge

Mermaid

Kevin Peter Hall

Big John

Jay Robinson

Cook

Kevin B. Kaplowitz

Child - Mr. Ryan

Jeffrey R. Shaw

Child - Otis

Marie Hawkins

Child - Pearl

Shea Joachim

Child - Sheriff

Molly Ann Carter

School Child

Myka Peck

School Child

Matthias Hues

Oscar - Lion Tamer

April Tatro

Human Pretzel

Roger Joseph Pugliese

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