Duplex

Drew Barrymore

Nancy Kendricks

Justin Theroux

Coop

Robert Wisdom

Officer Dan

Wallace Shawn

Herman

Christopher Doyle

Tavern Bartender

Michelle Krusiec

Dr. Kang

Maya Rudolph

Tara

Joey Banks

Police Officer

Ben Stiller

Alex Rose

Harvey Fierstein

Kenneth

James Remar

Chick

Louis Giambalvo

Pharmacist

Jenette Goldstein

Moderator

Tracey Walter

Pharmacy Customer

Danny DeVito

Narrator (voice) (uncredited)

Tim Maculan

Terrence

Christina Kirk

Mrs. Friedman

Philip Perlman

Phil

Edward Edwards

Antique Dealer

Amber Valletta

Celine

Kumar Pallana

Indian Restaurant Owner

Linda Porter

Old Biddy

Eileen Essell

Mrs. Connelly

Swoosie Kurtz

Jean

Cheryl Bartel

Ginger

Jackie Sandler

Bartender

Evgeniy Lazarev

Mr. Dzerzhinsky

Gary Riotto

Drug Dealer

Margie Loomis

Old Biddy

John Hamburg

Mr. Friedman

Leyna Nguyen

Newscaster

Chuma Gault

Mailroom Guy

Jim Castillo

Weatherman

Michael Fahn

Sneezer on Train

Roberta R. Deen

Caterer

Christine La Fontaine

Don Piper Fan

Geraldine Hughes

Receptionist

Picasso

Little Dick

Guiles

Little Dick

Bugsy

Little Dick

Maestro

Little Dick

Will Blomquist

College Student on Subway (uncredited)

Azizah Rowen

Barista (uncredited)

Larry Vigus

Man on Street (uncredited)